US-Ireland Business 2025

AmCham’s 2025 US-Ireland Business Report: ‘Succeeding Together: Driving Transatlantic Innovation and Trade’, tells the story of the resounding success and impact of the two-way US-Ireland business relationship. A success story that has resulted in job creation, in research and innovation, in the development of world-class talent and in the prosperity of both countries, with economic growth across both Ireland and the US continuing to outpace competitor jurisdictions.

This success is built off a two-way, mutually beneficial investment relationship, where Ireland is the 6th largest investor in the US and Irish companies now employ more than 118,000 people across all 50 US states. Meanwhile, there are more than 970 US companies employing 211,000 people across Ireland.

Throughout this report you will read contributions from business leaders and stakeholders in Ireland, the US and in Europe which highlight the competitive factors that draw US business to Ireland and explore how we can respond to the challenges and opportunities facing business to ensure the continued growth of the US-Ireland business relationship.

Contributors to the report include, An Taoiseach Micheál Martin, Government ministers, opposition TD’s, CEO of the US Chamber of Commerce – the world’s largest business organisation as well as stakeholders from across the EU and the US and the perspectives of almost 30 multinationals. The report also contains an economic analysis from leading economist Joseph Quinlan as well as industry insights from the AmCham President Liz Cunningham and leaders within the AmCham network. 

The thought leadership throughout the report addresses topics including Digitalisation, Supply Chains, RD&I, Climate Action, and Regional Development, and provide thought leadership on what Ireland and industry can do to be a leader in these areas.